Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Utrophin (Homo sapiens) | BDBM50519636 (BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assay | J Med Chem 63: 2547-2556 (2020) Article DOI: 10.1021/acs.jmedchem.9b01547 BindingDB Entry DOI: 10.7270/Q24B34P2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Utrophin (Homo sapiens) | BDBM50519636 (BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 187 | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Modulation of human utrophinA expressed in mouse H2K cells assessed as upregulation of utrophin production after 24 hrs by luciferase reporter gene a... | J Med Chem 63: 7880-7891 (2020) Article DOI: 10.1021/acs.jmedchem.0c00807 BindingDB Entry DOI: 10.7270/Q2G164DM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Utrophin (Homo sapiens) | BDBM50519636 (BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Activation of human utrophin-1 in iDMD cells by HTRF assay | J Med Chem 63: 2547-2556 (2020) Article DOI: 10.1021/acs.jmedchem.9b01547 BindingDB Entry DOI: 10.7270/Q24B34P2 | |||||||||||
More data for this Ligand-Target Pair |