Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae) | BDBM361339 (N1-(3-aminopropyl)-4-(6- aminopyridin-3-yl)-3-(2H-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.175 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ... | US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1 | |||||||||||
More data for this Ligand-Target Pair |