Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A' and Ligand = 'BDBM107714'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM107714 (US8598210, Table XV, 20 | US8722895, 20: {[5-(3-Cy...) Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(c1)[N+]#[C-] Show InChI InChI=1S/C15H11N3O4/c1-16-11-4-2-3-9(5-11)10-6-12(19)14(17-7-10)15(22)18-8-13(20)21/h2-7,19H,8H2,(H,18,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Akebia Therapeutics, Inc. US Patent									US Patent US9598370 (2017) BindingDB Entry DOI: 10.7270/Q20G3N64
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM107714 (US8598210, Table XV, 20 | US8722895, 20: {[5-(3-Cy...) Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(c1)[N+]#[C-] Show InChI InChI=1S/C15H11N3O4/c1-16-11-4-2-3-9(5-11)10-6-12(19)14(17-7-10)15(22)18-8-13(20)21/h2-7,19H,8H2,(H,18,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Akebia Therapeutics, Inc. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US8598210 (2013) BindingDB Entry DOI: 10.7270/Q2M04428
					More data for this Ligand-Target Pair