Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566616 (3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a- hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566616 (3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a- hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair |