Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM139606'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139606 (US8889870, 152 | US9388176, 152 | US9820989, 152) Show SMILES Cc1ccc(cc1N1CCc2ncncc2C1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H19F3N4O/c1-14-5-6-15(21(30)28-18-4-2-3-17(10-18)22(23,24)25)9-20(14)29-8-7-19-16(12-29)11-26-13-27-19/h2-6,9-11,13H,7-8,12H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139606 (US8889870, 152 | US9388176, 152 | US9820989, 152) Show SMILES Cc1ccc(cc1N1CCc2ncncc2C1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H19F3N4O/c1-14-5-6-15(21(30)28-18-4-2-3-17(10-18)22(23,24)25)9-20(14)29-8-7-19-16(12-29)11-26-13-27-19/h2-6,9-11,13H,7-8,12H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US8889870 (2014) BindingDB Entry DOI: 10.7270/Q25B0158
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139606 (US8889870, 152 | US9388176, 152 | US9820989, 152) Show SMILES Cc1ccc(cc1N1CCc2ncncc2C1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H19F3N4O/c1-14-5-6-15(21(30)28-18-4-2-3-17(10-18)22(23,24)25)9-20(14)29-8-7-19-16(12-29)11-26-13-27-19/h2-6,9-11,13H,7-8,12H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair