Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM139622'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139622 (US8889870, 170 | US9388176, 170 | US9820989, 170) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cncc3C(O)=O)c1 Show InChI InChI=1S/C25H25N3O3/c1-16(2)17-5-3-7-20(11-17)27-24(29)18-6-4-8-21(12-18)28-10-9-22-19(15-28)13-26-14-23(22)25(30)31/h3-8,11-14,16H,9-10,15H2,1-2H3,(H,27,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139622 (US8889870, 170 | US9388176, 170 | US9820989, 170) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cncc3C(O)=O)c1 Show InChI InChI=1S/C25H25N3O3/c1-16(2)17-5-3-7-20(11-17)27-24(29)18-6-4-8-21(12-18)28-10-9-22-19(15-28)13-26-14-23(22)25(30)31/h3-8,11-14,16H,9-10,15H2,1-2H3,(H,27,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US8889870 (2014) BindingDB Entry DOI: 10.7270/Q25B0158
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139622 (US8889870, 170 | US9388176, 170 | US9820989, 170) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cncc3C(O)=O)c1 Show InChI InChI=1S/C25H25N3O3/c1-16(2)17-5-3-7-20(11-17)27-24(29)18-6-4-8-21(12-18)28-10-9-22-19(15-28)13-26-14-23(22)25(30)31/h3-8,11-14,16H,9-10,15H2,1-2H3,(H,27,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair