Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM17686'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17686 (2-aminobenzimidazole, 11 | N-methyl-4-{[2-({3-[2-(...) Show SMILES CNC(=O)c1cc(Oc2ccc3nc(Nc4cc(OCCN5CCCC5)cc(c4)C(F)(F)F)[nH]c3c2)ccn1 Show InChI InChI=1S/C27H27F3N6O3/c1-31-25(37)24-16-20(6-7-32-24)39-19-4-5-22-23(15-19)35-26(34-22)33-18-12-17(27(28,29)30)13-21(14-18)38-11-10-36-8-2-3-9-36/h4-7,12-16H,2-3,8-11H2,1H3,(H,31,37)(H2,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	287	-37.0	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
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