Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM17692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM17692 (2-aminobenzimidazole, 17 | N-{4-chloro-3-[(4-methy...) Show SMILES CNc1nccc(Oc2ccc3nc(Nc4ccc(Cl)c(CN5CCN(C)CC5)c4)[nH]c3c2)n1 Show InChI InChI=1S/C24H27ClN8O/c1-26-23-27-8-7-22(31-23)34-18-4-6-20-21(14-18)30-24(29-20)28-17-3-5-19(25)16(13-17)15-33-11-9-32(2)10-12-33/h3-8,13-14H,9-12,15H2,1-2H3,(H,26,27,31)(H2,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	40	-41.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Amgen					Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...				J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74
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