Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM181035'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM181035 (US9133183, Example 101) Show SMILES CN(C)C(=O)Nc1cc(Oc2cc(F)c(NC(=O)N3CCN(C4CCOCC4)C3=O)cc2Cl)ccn1 Show InChI InChI=1S/C23H26ClFN6O5/c1-29(2)21(32)28-20-11-15(3-6-26-20)36-19-13-17(25)18(12-16(19)24)27-22(33)31-8-7-30(23(31)34)14-4-9-35-10-5-14/h3,6,11-14H,4-5,7-10H2,1-2H3,(H,27,33)(H,26,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+3	n/a	n/a	n/a	n/a	n/a	27
Deciphera Pharmaceuticals, LLC US Patent					Assay Description These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...				US Patent US9133183 (2015) BindingDB Entry DOI: 10.7270/Q2DN43TD
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