Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM21109'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21109 (3-{4-[3-amino-7-(trifluoromethoxy)-1,2-benzoxazol-...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2ccc(OC(F)(F)F)c3onc(N)c23)c1 Show InChI InChI=1S/C22H16F4N4O3/c1-11-2-8-15(23)16(10-11)29-21(31)28-13-5-3-12(4-6-13)14-7-9-17(32-22(24,25)26)19-18(14)20(27)30-33-19/h2-10H,1H3,(H2,27,30)(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	179	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair