Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM365366'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365366 (US10633373, Example 71 | US10669265, Example 71 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C32H38FN5O7S/c1-21-10-15-26(33)27(18-21)37-32(42)36-24-13-11-22(12-14-24)25-19-23(20-35-30(25)34)31(41)38-46(43,16-6-4-8-28(39)44-2)17-7-5-9-29(40)45-3/h10-15,18-20H,4-9,16-17H2,1-3H3,(H2,34,35)(H2,36,37,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Allergan, Inc. US Patent					Assay Description VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...				US Patent US10633373 (2020) BindingDB Entry DOI: 10.7270/Q2Z60S37
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365366 (US10633373, Example 71 | US10669265, Example 71 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C32H38FN5O7S/c1-21-10-15-26(33)27(18-21)37-32(42)36-24-13-11-22(12-14-24)25-19-23(20-35-30(25)34)31(41)38-46(43,16-6-4-8-28(39)44-2)17-7-5-9-29(40)45-3/h10-15,18-20H,4-9,16-17H2,1-3H3,(H2,34,35)(H2,36,37,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US10669265 (2020) BindingDB Entry DOI: 10.7270/Q20R9SFZ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365366 (US10633373, Example 71 | US10669265, Example 71 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C32H38FN5O7S/c1-21-10-15-26(33)27(18-21)37-32(42)36-24-13-11-22(12-14-24)25-19-23(20-35-30(25)34)31(41)38-46(43,16-6-4-8-28(39)44-2)17-7-5-9-29(40)45-3/h10-15,18-20H,4-9,16-17H2,1-3H3,(H2,34,35)(H2,36,37,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair