Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM373143'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM373143 (FD-2013015 | US9902709, Compound Example 1) Show SMILES Cn1cc(cn1)-c1nccc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c1F Show InChI InChI=1S/C23H16ClF4N5O2/c1-33-12-13(11-30-33)21-20(25)19(8-9-29-21)35-16-5-2-14(3-6-16)31-22(34)32-15-4-7-18(24)17(10-15)23(26,27)28/h2-12H,1H3,(H2,31,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q2T43WF5
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