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Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM373150'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM373150
PNG
(FD-2013024 | US9902709, Compound Example 3)
Show SMILES Cn1cc(cn1)-c1nccc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)c1Cl
Show InChI InChI=1S/C23H15Cl2F4N5O2/c1-34-11-12(10-31-34)21-20(25)19(6-7-30-21)36-14-3-5-18(17(26)9-14)33-22(35)32-13-2-4-16(24)15(8-13)23(27,28)29/h2-11H,1H3,(H2,32,33,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 222n/an/an/an/an/an/a



University of Mississippi



Assay Description
Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...


J Med Chem 48: 2906-15 (2005)


BindingDB Entry DOI: 10.7270/Q2T43WF5
More data for this
Ligand-Target Pair