Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM4619'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4619 (Anilinoquinazoline deriv. 2 | CHEMBL1204360 | CHEM...) Show SMILES COc1cc2ncnc(Nc3ccccc3F)c2cc1OC Show InChI InChI=1S/C16H14FN3O2/c1-21-14-7-10-13(8-15(14)22-2)18-9-19-16(10)20-12-6-4-3-5-11(12)17/h3-9H,1-2H3,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiaotong University Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 2126-33 (2007) Article DOI: 10.1016/j.bmcl.2007.01.089 BindingDB Entry DOI: 10.7270/Q2S1839D
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4619 (Anilinoquinazoline deriv. 2 | CHEMBL1204360 | CHEM...) Show SMILES COc1cc2ncnc(Nc3ccccc3F)c2cc1OC Show InChI InChI=1S/C16H14FN3O2/c1-21-14-7-10-13(8-15(14)22-2)18-9-19-16(10)20-12-6-4-3-5-11(12)17/h3-9H,1-2H3,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	25
AstraZeneca					Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...				J Med Chem 42: 5369-89 (1999) Article DOI: 10.1021/jm990345w BindingDB Entry DOI: 10.7270/Q2F47MBM
					More data for this Ligand-Target Pair