Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50002592'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002592 (CHEMBL2113188) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(c4ccccc4)C(F)(F)F)=CC3=O)c2cc1OC |c:30,t:13| Show InChI InChI=1S/C26H22F3N3O6/c1-35-8-9-37-23-12-17-16(10-22(23)36-2)25(31-14-30-17)32-18-11-20(34)21(13-19(18)33)38-24(26(27,28)29)15-6-4-3-5-7-15/h3-7,10-14,24H,8-9H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002592 (CHEMBL2113188) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(c4ccccc4)C(F)(F)F)=CC3=O)c2cc1OC |c:30,t:13| Show InChI InChI=1S/C26H22F3N3O6/c1-35-8-9-37-23-12-17-16(10-22(23)36-2)25(31-14-30-17)32-18-11-20(34)21(13-19(18)33)38-24(26(27,28)29)15-6-4-3-5-7-15/h3-7,10-14,24H,8-9H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP and in presence of 5% mouse plasma				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002592 (CHEMBL2113188) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(c4ccccc4)C(F)(F)F)=CC3=O)c2cc1OC |c:30,t:13| Show InChI InChI=1S/C26H22F3N3O6/c1-35-8-9-37-23-12-17-16(10-22(23)36-2)25(31-14-30-17)32-18-11-20(34)21(13-19(18)33)38-24(26(27,28)29)15-6-4-3-5-7-15/h3-7,10-14,24H,8-9H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP and in presence of 100 uM glutathione				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002592 (CHEMBL2113188) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(c4ccccc4)C(F)(F)F)=CC3=O)c2cc1OC |c:30,t:13| Show InChI InChI=1S/C26H22F3N3O6/c1-35-8-9-37-23-12-17-16(10-22(23)36-2)25(31-14-30-17)32-18-11-20(34)21(13-19(18)33)38-24(26(27,28)29)15-6-4-3-5-7-15/h3-7,10-14,24H,8-9H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair