Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged VEGFR2 cytoplasmic domain (789 to1356 residues) expressed in baculovirus expression system by Z'-LYTE assa... | Bioorg Med Chem Lett 26: 5947-5950 (2016) Article DOI: 10.1016/j.bmcl.2016.10.087 BindingDB Entry DOI: 10.7270/Q29888Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, Inc. Curated by ChEMBL | Assay Description Inhibition of human N-terminal 6His-tagged VEGFR2 (807 to 1171 residues) expressed in Sf9 insect cells using 5-carboxyfluorescein(FAM)-EEPLYWSFPAKKK-... | Bioorg Med Chem Lett 26: 5947-5950 (2016) Article DOI: 10.1016/j.bmcl.2016.10.087 BindingDB Entry DOI: 10.7270/Q29888Z2 | |||||||||||
More data for this Ligand-Target Pair |