BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50212001'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50212001
PNG
(CHEMBL233829 | N-(3-chloro-4-(trifluoromethyl)phen...)
Show SMILES FC(F)(F)c1ccc(NC(=O)c2nnnn2CCc2ccncc2)cc1Cl
Show InChI InChI=1S/C16H12ClF3N6O/c17-13-9-11(1-2-12(13)16(18,19)20)22-15(27)14-23-24-25-26(14)8-5-10-3-6-21-7-4-10/h1-4,6-7,9H,5,8H2,(H,22,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Chemical Diversity, Inc.

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA


Bioorg Med Chem Lett 17: 3550-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50212001
PNG
(CHEMBL233829 | N-(3-chloro-4-(trifluoromethyl)phen...)
Show SMILES FC(F)(F)c1ccc(NC(=O)c2nnnn2CCc2ccncc2)cc1Cl
Show InChI InChI=1S/C16H12ClF3N6O/c17-13-9-11(1-2-12(13)16(18,19)20)22-15(27)14-23-24-25-26(14)8-5-10-3-6-21-7-4-10/h1-4,6-7,9H,5,8H2,(H,22,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Chemical Diversity, Inc.

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 17: 3550-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N
More data for this
Ligand-Target Pair