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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50243075'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50243075
PNG
(4-methyl-N3-(pyridin-3-yl)-N1-(3-(trifluoromethyl)...)
Show SMILES Cc1ccc(cc1C(=O)Nc1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H16F3N3O2/c1-13-7-8-14(10-18(13)20(29)27-17-6-3-9-25-12-17)19(28)26-16-5-2-4-15(11-16)21(22,23)24/h2-12H,1H3,(H,26,28)(H,27,29)
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Article
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n/an/a 294n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of KDR (unknown origin)

Bioorg Med Chem Lett 18: 4137-41 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.089
BindingDB Entry DOI: 10.7270/Q20001WP
More data for this
Ligand-Target Pair