BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vasopressin V1a receptor' and Ligand = 'BDBM35666'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35666 (BMC173130 Compound 1t \| benzazepinelidene acetamid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	28	-43.1	n/a	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc.					Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...				Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM
Astellas Pharma Inc.					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35666 (BMC173130 Compound 1t \| benzazepinelidene acetamid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	28	-42.8	n/a	n/a	n/a	n/a	n/a	7.4	23
Astellas Pharma Inc.					Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...				Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW
Astellas Pharma Inc.					More data for this Ligand-Target Pair