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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vasopressin V1a receptor' and Ligand = 'BDBM50354887'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vasopressin V1a receptor


(Homo sapiens (Human))		BDBM50354887
PNG
(CHEMBL1837025)
Show SMILES CN1CCN(Cc2nnc(C3CCN(CC3)c3ccccn3)n2Cc2ccccc2)CC1
Show InChI InChI=1S/C25H33N7/c1-29-15-17-30(18-16-29)20-24-27-28-25(32(24)19-21-7-3-2-4-8-21)22-10-13-31(14-11-22)23-9-5-6-12-26-23/h2-9,12,22H,10-11,13-20H2,1H3
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Article
PubMed
n/an/a 609n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...

Bioorg Med Chem Lett 21: 5684-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.038
BindingDB Entry DOI: 10.7270/Q2TB179T
More data for this
Ligand-Target Pair