Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM35672'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35672 (benzazepinelidene acetamide derivative, 1g) Show SMILES C[C@H]1CCN(C1)c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(=O)NCCO)c3ccccc23)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C27H28F5N3O3/c1-17-8-11-34(16-17)18-6-7-20(22(14-18)27(30,31)32)25(38)35-12-9-26(28,29)21(15-24(37)33-10-13-36)19-4-2-3-5-23(19)35/h2-7,14-15,17,36H,8-13,16H2,1H3,(H,33,37)/b21-15-/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	14	-44.5	n/a	n/a	n/a	n/a	n/a	7.4	23
Astellas Pharma Inc.					Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...				Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW
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