BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM50177593'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to V2 receptor (unknown origin)				J Med Chem 61: 8670-8692 (2018) Article DOI: 10.1021/acs.jmedchem.8b00697 BindingDB Entry DOI: 10.7270/Q24J0HRF
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human vasopressin V2 receptor expressed in CHO cells				J Med Chem 53: 1546-62 (2010) Article DOI: 10.1021/jm901084f BindingDB Entry DOI: 10.7270/Q2FX7BD4
UMR 7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from human V2 receptor expressed in CHO cell membranes by radioligand binding assay				J Med Chem 61: 8670-8692 (2018) Article DOI: 10.1021/acs.jmedchem.8b00697 BindingDB Entry DOI: 10.7270/Q24J0HRF
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human V2 receptor transfected in LV2 cells				Bioorg Med Chem Lett 16: 954-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.107 BindingDB Entry DOI: 10.7270/Q27945GR
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	80.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human vasopressin V2 receptor expressed in mouse LV2 cells				Bioorg Med Chem Lett 17: 5796-800 (2007) Article DOI: 10.1016/j.bmcl.2007.08.053 BindingDB Entry DOI: 10.7270/Q2NV9J05
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Agonist activity at V2 receptor (unknown origin) by cAMP accumulation assay				J Med Chem 61: 8670-8692 (2018) Article DOI: 10.1021/acs.jmedchem.8b00697 BindingDB Entry DOI: 10.7270/Q24J0HRF
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	39.9	n/a	n/a	n/a	n/a
UMR 7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Activity at human vasopressin V2 receptor expressed in CHO cells by NFAT-luciferase gene reporter assay				J Med Chem 53: 1546-62 (2010) Article DOI: 10.1021/jm901084f BindingDB Entry DOI: 10.7270/Q2FX7BD4
UMR 7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50177593 ((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	0.740	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding to human V2 receptor expressed in LV2 cells by cAMP production				Bioorg Med Chem Lett 16: 954-9 (2006) Article DOI: 10.1016/j.bmcl.2005.10.107 BindingDB Entry DOI: 10.7270/Q27945GR
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair