BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vitamin D3 receptor' and Ligand = 'BDBM50292315'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vitamin D3 receptor (Rattus norvegicus)	BDBM50292315 ((5R,8aR,Z)-7-((E)-2-((3aS,7aR)-1-((R)-6-hydroxy-6-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of 1-alpha,25-dihydroxyvitamin from rat recombinant VDR				J Med Chem 50: 6154-64 (2007) Article DOI: 10.1021/jm070635+ BindingDB Entry DOI: 10.7270/Q2DB82PM
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Rattus norvegicus)	BDBM50292315 ((5R,8aR,Z)-7-((E)-2-((3aS,7aR)-1-((R)-6-hydroxy-6-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Activity at VDR in rat osteosarcoma cells assessed as 24-hydroxylase transcription by reporter gene assay				J Med Chem 50: 6154-64 (2007) Article DOI: 10.1021/jm070635+ BindingDB Entry DOI: 10.7270/Q2DB82PM
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair