Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vitamin D3 receptor' and Ligand = 'BDBM50389863'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50389863 (CHEMBL2070862) Show SMILES COc1ccc(cc1)C(Nc1ccccc1)c1c(C)[nH]c2ccccc12 Show InChI InChI=1S/C23H22N2O/c1-16-22(20-10-6-7-11-21(20)24-16)23(25-18-8-4-3-5-9-18)17-12-14-19(26-2)15-13-17/h3-15,23-25H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of CMV-VDR expressed in human HEK293T cells assessed as inhibition of 1,25-(OH)2D3-induced CYP24A1 promoter transcription after 16 hrs by ...				J Med Chem 55: 4640-51 (2012) Article DOI: 10.1021/jm300460c BindingDB Entry DOI: 10.7270/Q2HD7WRP
					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50389863 (CHEMBL2070862) Show SMILES COc1ccc(cc1)C(Nc1ccccc1)c1c(C)[nH]c2ccccc12 Show InChI InChI=1S/C23H22N2O/c1-16-22(20-10-6-7-11-21(20)24-16)23(25-18-8-4-3-5-9-18)17-12-14-19(26-2)15-13-17/h3-15,23-25H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 after 3 hrs by fluorescence polarization assay				J Med Chem 55: 4640-51 (2012) Article DOI: 10.1021/jm300460c BindingDB Entry DOI: 10.7270/Q2HD7WRP
					More data for this Ligand-Target Pair