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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1' and Ligand = 'BDBM50481462'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1


(Homo sapiens (Human))		BDBM50481462
PNG
(CHEMBL597782)
Show SMILES CN1CCC(CC1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C32H38ClN3O/c1-34-18-16-28(17-19-34)32(27-12-14-29(33)15-13-27)36-22-20-35(21-23-36)31(37)24-30(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-15,28,30,32H,16-24H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Neuromed Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method

Bioorg Med Chem Lett 20: 1378-83 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR
More data for this
Ligand-Target Pair