Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human)) | BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Displacement of [3H]nitrendipine from L-type calcium channel of bovine frontal cortex membranes. | J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human)) | BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human)) | BDBM50004633 ((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Displacement of [3H]-diltiazem from L-type calcium channel of bovine frontal cortex membranes. | J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8 | |||||||||||
More data for this Ligand-Target Pair |