Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1D' and Ligand = 'BDBM50317805'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50317805 (3-but-3-ynyl 5-methyl 2,6-dimethyl-4-(3-nitropheny...) Show SMILES COC(=O)C1C(C(C(=O)OCCC#C)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |c:16,t:13| Show InChI InChI=1S/C20H20N2O6/c1-5-6-10-28-20(24)17-13(3)21-12(2)16(19(23)27-4)18(17)14-8-7-9-15(11-14)22(25)26/h1,7-9,11,16,18H,6,10H2,2-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay				Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90
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