Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1D' and Ligand = 'BDBM50422192'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50422192 (CHEMBL25278) Show SMILES COc1ccc(cc1)[C@@H]1Sc2c(Cl)cccc2-n2c(CN(C)C)ccc2[C@@H]1OC(C)=O Show InChI InChI=1S/C24H25ClN2O3S/c1-15(28)30-22-20-13-10-17(14-26(2)3)27(20)21-7-5-6-19(25)24(21)31-23(22)16-8-11-18(29-4)12-9-16/h5-13,22-23H,14H2,1-4H3/t22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50				J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M
					More data for this Ligand-Target Pair