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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50227619'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1S


(Rattus norvegicus)		BDBM50227619
PNG
(CHEMBL44275)
Show SMILES CCO\C(O)=C1\[C@H]([C@H](C(=O)OCC)\C(=C\C(=O)c2ccccc2)N=C1C)c1cccc(Cl)c1Cl |c:24|
Show InChI InChI=1S/C26H25Cl2NO5/c1-4-33-25(31)21-15(3)29-19(14-20(30)16-10-7-6-8-11-16)23(26(32)34-5-2)22(21)17-12-9-13-18(27)24(17)28/h6-14,22-23,31H,4-5H2,1-3H3/b19-14-,25-21+/t22-,23-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 28n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of [3H]nitrendipine binding to calcium channels in the rat brain.

J Med Chem 31: 1659-64 (1988)


BindingDB Entry DOI: 10.7270/Q2WQ060D
More data for this
Ligand-Target Pair