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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1' and Ligand = 'BDBM50481858'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1


(Rattus norvegicus-Rattus norvegicus (Rat))		BDBM50481858
PNG
(CHEMBL1086621)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCN(CCCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C32H38F2N2O4/c1-38-29-21-25(22-30(39-2)31(29)40-3)32(37)36-19-17-35(18-20-36)16-6-4-5-7-28(23-8-12-26(33)13-9-23)24-10-14-27(34)15-11-24/h8-15,21-22,28H,4-7,16-20H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



University of Calgary

Curated by ChEMBL


Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...

Bioorg Med Chem Lett 19: 6467-72 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57
More data for this
Ligand-Target Pair