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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit beta-1' and Ligand = 'BDBM50481495'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-1


(Homo sapiens)		BDBM50481495
PNG
(CHEMBL599822)
Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)CN(c2ccccc2)c2ccccc2)c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C31H29Cl2N3O/c32-25-16-17-28(29(33)22-25)31(24-10-4-1-5-11-24)35-20-18-34(19-21-35)30(37)23-36(26-12-6-2-7-13-26)27-14-8-3-9-15-27/h1-17,22,31H,18-21,23H2
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 460n/an/an/an/an/an/a



Neuromed Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...

Bioorg Med Chem Lett 20: 1378-83 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR
More data for this
Ligand-Target Pair