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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1' and Ligand = 'BDBM246334'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1


(Homo sapiens (Human))		BDBM246334
PNG
(US9434693, 29)
Show SMILES CON(C)C(=O)N1CC(C1)Oc1cc(-c2ccc(Cl)cc2)n(n1)-c1ccccc1OC
Show InChI InChI=1S/C22H23ClN4O4/c1-25(30-3)22(28)26-13-17(14-26)31-21-12-19(15-8-10-16(23)11-9-15)27(24-21)18-6-4-5-7-20(18)29-2/h4-12,17H,13-14H2,1-3H3
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US Patent
n/an/a 14n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...

US Patent US9434693 (2016)


BindingDB Entry DOI: 10.7270/Q29S1PZJ
More data for this
Ligand-Target Pair