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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1' and Ligand = 'BDBM246348'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1


(Homo sapiens (Human))		BDBM246348
PNG
(US9434693, 43)
Show SMILES COc1ccccc1-n1nc(OC2CC(C)(C)OC(C)(C)C2)cc1-c1ccc(cc1)C#N
Show InChI InChI=1S/C26H29N3O3/c1-25(2)15-20(16-26(3,4)32-25)31-24-14-22(19-12-10-18(17-27)11-13-19)29(28-24)21-8-6-7-9-23(21)30-5/h6-14,20H,15-16H2,1-5H3
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US Patent
n/an/a 7.20n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...

US Patent US9434693 (2016)


BindingDB Entry DOI: 10.7270/Q29S1PZJ
More data for this
Ligand-Target Pair