BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50200825'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50200825
PNG
(CHEMBL3972616)
Show SMILES C[C@@H]1CN(Cc2cnc(s2)C(F)(F)F)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 |r|
Show InChI InChI=1S/C22H22F3N5OS/c1-14-12-29(13-17-11-27-20(32-17)22(23,24)25)19-8-4-3-7-18(19)15(2)30(14)21(31)28-16-6-5-9-26-10-16/h3-11,14-15H,12-13H2,1-2H3,(H,28,31)/t14-,15+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 42n/an/an/an/an/an/a



Actelion Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...

J Med Chem 59: 10661-10675 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01356
BindingDB Entry DOI: 10.7270/Q2RV0QN8
More data for this
Ligand-Target Pair