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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50200902'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50200902
PNG
(CHEMBL3939715)
Show SMILES C[C@@H]1CN(CCOC(C)(C)C)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 |r|
Show InChI InChI=1S/C25H35N3O2/c1-19-18-27(15-16-30-25(3,4)5)23-14-10-9-13-22(23)20(2)28(19)24(29)26-17-21-11-7-6-8-12-21/h6-14,19-20H,15-18H2,1-5H3,(H,26,29)/t19-,20+/m1/s1
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Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Actelion Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...

J Med Chem 59: 10661-10675 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01356
BindingDB Entry DOI: 10.7270/Q2RV0QN8
More data for this
Ligand-Target Pair