Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50322955'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322955 (1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-isobut...) Show SMILES CC(C)CN1CC2(CCN(CC2)C(=O)Nc2cc(F)cc(F)c2)C1c1ccc(Cl)cc1 Show InChI InChI=1S/C24H28ClF2N3O/c1-16(2)14-30-15-24(22(30)17-3-5-18(25)6-4-17)7-9-29(10-8-24)23(31)28-21-12-19(26)11-20(27)13-21/h3-6,11-13,16,22H,7-10,14-15H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair