Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent calcium channel gamma-8 subunit' and Ligand = 'BDBM288281'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-8 subunit (Homo sapiens (Human))	BDBM288281 (5-(2-Cyclopropyl-8-methyl-6-(trifluoromethyl)- | U...) Show SMILES Cc1cc(cc2CC(=O)Nc12)-c1c(cc(C)c2nc(nn12)C1CC1)C(F)(F)F Show InChI InChI=1S/C20H17F3N4O/c1-9-5-13(7-12-8-15(28)24-16(9)12)17-14(20(21,22)23)6-10(2)19-25-18(11-3-4-11)26-27(17)19/h5-7,11H,3-4,8H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.251	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...				US Patent US10087185 (2018) BindingDB Entry DOI: 10.7270/Q2QZ2D0H
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