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Found 1 hit Enz. Inhib. hit(s) with Target = 'WD repeat-containing protein 48' and Ligand = 'BDBM352015'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM352015
PNG
(US9802904, 76)
Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCC2CCN(CC2)c2cnccn2)n1
Show InChI InChI=1S/C24H30N6/c1-17(2)20-6-4-5-7-21(20)24-27-14-18(3)23(29-24)28-15-19-8-12-30(13-9-19)22-16-25-10-11-26-22/h4-7,10-11,14,16-17,19H,8-9,12-13,15H2,1-3H3,(H,27,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay

J Med Chem 57: 8099-110 (2014)


Article DOI: 10.1021/jm5010495
BindingDB Entry DOI: 10.7270/Q24X5BSH
More data for this
Ligand-Target Pair