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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'WD repeat-containing protein 48' and Ligand = 'BDBM50497320'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM50497320
PNG
(CHEMBL3356515)
Show SMILES Cc1cnc(nc1NCc1ccc(cc1)-n1ccnn1)-c1ccccc1C1CCC1
Show InChI InChI=1S/C24H24N6/c1-17-15-25-24(22-8-3-2-7-21(22)19-5-4-6-19)28-23(17)26-16-18-9-11-20(12-10-18)30-14-13-27-29-30/h2-3,7-15,19H,4-6,16H2,1H3,(H,25,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 180n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay

J Med Chem 57: 8099-110 (2014)


Article DOI: 10.1021/jm5010495
BindingDB Entry DOI: 10.7270/Q24X5BSH
More data for this
Ligand-Target Pair