BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'WD repeat-containing protein 48' and Ligand = 'BDBM50497332'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM50497332
PNG
(CHEMBL3185465)
Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2cccnc2)c2cccn2n1
Show InChI InChI=1S/C27H25N5/c1-19(2)23-8-3-4-9-24(23)26-30-27(25-10-6-16-32(25)31-26)29-17-20-11-13-21(14-12-20)22-7-5-15-28-18-22/h3-16,18-19H,17H2,1-2H3,(H,29,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 260n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay

J Med Chem 57: 8099-110 (2014)


Article DOI: 10.1021/jm5010495
BindingDB Entry DOI: 10.7270/Q24X5BSH
More data for this
Ligand-Target Pair