Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'WD repeat-containing protein 5 [24-334]' and Ligand = 'BDBM200643'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 [24-334] (Homo sapiens (Human))	BDBM200643 (US9233086, 1C) Show SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C16H31N7O4/c1-8(2)12(22-10(4)24)15(27)23-11(6-5-7-20-16(18)19)14(26)21-9(3)13(17)25/h8-9,11-12H,5-7H2,1-4H3,(H2,17,25)(H,21,26)(H,22,24)(H,23,27)(H4,18,19,20)/t9-,11-,12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	6.5	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description N-terminal His-tagged WDR5Δ23 (residues 24-334) was expressed from the pET28-MHL vector in Rosetta2(DE3) pLysS cells (Novagen). Cells were grown...				US Patent US9233086 (2016) BindingDB Entry DOI: 10.7270/Q27943GX
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