Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM127921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM127921 (US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...) Show SMILES Cc1ccc(C)n2nc(CCc3cn4Cc5ccccc5-c4n3)nc12 Show InChI InChI=1S/C20H19N5/c1-13-7-8-14(2)25-19(13)22-18(23-25)10-9-16-12-24-11-15-5-3-4-6-17(15)20(24)21-16/h3-8,12H,9-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US8796304 (2014) BindingDB Entry DOI: 10.7270/Q2FN14WW
					More data for this Ligand-Target Pair