Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM127928'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM127928 (US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...) Show SMILES Cc1cnc(C)c2nc(CCc3cn4Cc5ccc(F)cc5-c4n3)nn12 Show InChI InChI=1S/C19H17FN6/c1-11-8-21-12(2)18-23-17(24-26(11)18)6-5-15-10-25-9-13-3-4-14(20)7-16(13)19(25)22-15/h3-4,7-8,10H,5-6,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US8796304 (2014) BindingDB Entry DOI: 10.7270/Q2FN14WW
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