Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM147147'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM147147 (US8957077, 1-25) Show SMILES Cc1nc(C)c(CNc2cc(nc3ccnn23)C(=O)NCCc2ccccn2)s1 Show InChI InChI=1S/C20H21N7OS/c1-13-17(29-14(2)25-13)12-23-19-11-16(26-18-7-10-24-27(18)19)20(28)22-9-6-15-5-3-4-8-21-15/h3-5,7-8,10-11,23H,6,9,12H2,1-2H3,(H,22,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...				US Patent US8957077 (2015) BindingDB Entry DOI: 10.7270/Q29G5KHW
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