Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM156263'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156263 (US9018217, [2-(5,7-Dimethyl-imidazo[1,2-a]pyrimidi...) Show SMILES Cc1cc(C)n2cc(CSc3nc(cn3CC#N)-c3ccccc3)nc2n1 Show InChI InChI=1S/C20H18N6S/c1-14-10-15(2)26-11-17(23-19(26)22-14)13-27-20-24-18(12-25(20)9-8-21)16-6-4-3-5-7-16/h3-7,10-12H,9,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156263 (US9018217, [2-(5,7-Dimethyl-imidazo[1,2-a]pyrimidi...) Show SMILES Cc1cc(C)n2cc(CSc3nc(cn3CC#N)-c3ccccc3)nc2n1 Show InChI InChI=1S/C20H18N6S/c1-14-10-15(2)26-11-17(23-19(26)22-14)13-27-20-24-18(12-25(20)9-8-21)16-6-4-3-5-7-16/h3-7,10-12H,9,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair