Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM156347'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156347 (US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...) Show SMILES CC(C)Cn1cc(nc1CCc1nc2nc(C)cc(C)n2n1)-c1ccccc1 Show InChI InChI=1S/C22H26N6/c1-15(2)13-27-14-19(18-8-6-5-7-9-18)24-21(27)11-10-20-25-22-23-16(3)12-17(4)28(22)26-20/h5-9,12,14-15H,10-11,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156347 (US9018217, 2-[2-(1-Isobutyl-4-phenyl-1H-imidazol-2...) Show SMILES CC(C)Cn1cc(nc1CCc1nc2nc(C)cc(C)n2n1)-c1ccccc1 Show InChI InChI=1S/C22H26N6/c1-15(2)13-27-14-19(18-8-6-5-7-9-18)24-21(27)11-10-20-25-22-23-16(3)12-17(4)28(22)26-20/h5-9,12,14-15H,10-11,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair