Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM156353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156353 (US9018217, 8-fluoro-2-(2-(1-methyl-4-phenyl-1H-imi...) Show SMILES Cn1cc(nc1CCc1nc2c(F)cccn2n1)-c1ccccc1 Show InChI InChI=1S/C18H16FN5/c1-23-12-15(13-6-3-2-4-7-13)20-17(23)10-9-16-21-18-14(19)8-5-11-24(18)22-16/h2-8,11-12H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156353 (US9018217, 8-fluoro-2-(2-(1-methyl-4-phenyl-1H-imi...) Show SMILES Cn1cc(nc1CCc1nc2c(F)cccn2n1)-c1ccccc1 Show InChI InChI=1S/C18H16FN5/c1-23-12-15(13-6-3-2-4-7-13)20-17(23)10-9-16-21-18-14(19)8-5-11-24(18)22-16/h2-8,11-12H,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair