Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM173111'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173111 (US9096589, 1-(4-Chloro-phenyl)-2-{2-[2-(5,7-dimeth...) Show SMILES Cc1cc(C)n2cc(CCc3nc(cn3CC(O)c3ccc(Cl)cc3)-c3cncs3)nc2n1 Show InChI InChI=1S/C24H23ClN6OS/c1-15-9-16(2)31-11-19(28-24(31)27-15)7-8-23-29-20(22-10-26-14-33-22)12-30(23)13-21(32)17-3-5-18(25)6-4-17/h3-6,9-12,14,21,32H,7-8,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
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