Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM201555'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM201555 (US9540384, 4 | methyl-{6-[2-(1-methyl-4-phenyl-1h-...) Show SMILES CNc1cccc(CCc2nc(cn2C)-c2ccccc2)n1 Show InChI InChI=1S/C18H20N4/c1-19-17-10-6-9-15(20-17)11-12-18-21-16(13-22(18)2)14-7-4-3-5-8-14/h3-10,13H,11-12H2,1-2H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	25
Hoffmann-La Roche, Inc. US Patent					Assay Description The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...				US Patent US9540384 (2017) BindingDB Entry DOI: 10.7270/Q2HT2MG1
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