Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM202027'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM202027 (4-(2-(pyridin-3-yl)-6-((6-(pyrrolidin-1-yl)pyridin...) Show SMILES C(Oc1cc(nc(n1)-c1cccnc1)N1CCOCC1)c1cccc(n1)N1CCCC1 Show InChI InChI=1S/C23H26N6O2/c1-2-10-28(9-1)20-7-3-6-19(25-20)17-31-22-15-21(29-11-13-30-14-12-29)26-23(27-22)18-5-4-8-24-16-18/h3-8,15-16H,1-2,9-14,17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	25
Hoffmann-La Roche, Inc. US Patent					Assay Description The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...				US Patent US9540384 (2017) BindingDB Entry DOI: 10.7270/Q2HT2MG1
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